| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 23, 2005 | 10–20 | Cardinals +10 | Titans +0.4 | Regular Season | |
| Oct 23, 2005 | 6–10 | Bears +4 | Ravens +0.7 | Regular Season | |
| Oct 23, 2005 | 17–38 | Raiders +21 | Bills +3.4 | Regular Season | |
| Oct 23, 2005 | 23–24 | Giants +1 | Broncos +2.2 | Regular Season | |
| Oct 23, 2005 | 10–13 | Seahawks +3 | Seahawks +3.5 | Regular Season | |
| Oct 23, 2005 | 13–10 | Lions +3 | Browns +2.1 | Regular Season | |
| Oct 23, 2005 | 38–20 | Colts +18 | Colts +9.4 | Regular Season | |
| Oct 23, 2005 | 17–52 | Commanders +35 | Commanders +8.1 | Regular Season | |
| Oct 23, 2005 | 27–13 | Steelers +14 | Bengals +0.4 | Regular Season | |
| Oct 23, 2005 | 17–20 | Eagles +3 | Eagles +2.9 | Regular Season | |
| Oct 23, 2005 | 17–28 | Rams +11 | Rams +4.3 | Regular Season | |
| Oct 23, 2005 | 20–23 | Vikings +3 | Packers +0.3 | Regular Season |