| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Dec 4, 2005 | 10–34 | Chargers +24 | Chargers +12.2 | Regular Season | |
| Dec 4, 2005 | 27–31 | Chiefs +4 | Broncos +0.3 | Regular Season | |
| Dec 4, 2005 | 3–16 | Patriots +13 | Patriots +11.0 | Regular Season | |
| Dec 4, 2005 | 17–10 | Cardinals +7 | Cardinals +0.3 | Regular Season | |
| Dec 4, 2005 | 24–9 | Commanders +15 | Rams +4.6 | Regular Season | |
| Dec 4, 2005 | 7–19 | Bears +12 | Bears +4.1 | Regular Season | |
| Dec 4, 2005 | 10–3 | Buccaneers +7 | Buccaneers +1.7 | Regular Season | |
| Dec 4, 2005 | 6–24 | Panthers +18 | Panthers +3.8 | Regular Season | |
| Dec 4, 2005 | 23–24 | Dolphins +1 | Dolphins +2.0 | Regular Season | |
| Dec 4, 2005 | 20–14 | Jaguars +6 | Jaguars +4.4 | Regular Season | |
| Dec 4, 2005 | 10–17 | Giants +7 | Giants +4.3 | Regular Season | |
| Dec 4, 2005 | 15–16 | Ravens +1 | Ravens +8.0 | Regular Season | |
| Dec 4, 2005 | 38–31 | Bengals +7 | Steelers +5.4 | Regular Season | |
| Dec 4, 2005 | 21–16 | Vikings +5 | Vikings +2.1 | Regular Season | |
| Dec 4, 2005 | 3–35 | Colts +32 | Colts +16.3 | Regular Season |