| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 1, 2006 | 6–37 | Bears +31 | Seahawks +0.3 | Regular Season | |
| Oct 1, 2006 | 38–13 | Patriots +25 | Bengals +2.5 | Regular Season | |
| Oct 1, 2006 | 24–21 | Browns +3 | Raiders +2.4 | Regular Season | |
| Oct 1, 2006 | 30–36 | Commanders +6 | Commanders +1.3 | Regular Season | |
| Oct 1, 2006 | 34–41 | Rams +7 | Rams +7.3 | Regular Season | |
| Oct 1, 2006 | 45–14 | Cowboys +31 | Cowboys +2.4 | Regular Season | |
| Oct 1, 2006 | 10–32 | Falcons +22 | Falcons +8.1 | Regular Season | |
| Oct 1, 2006 | 13–16 | Ravens +3 | Chargers +0.3 | Regular Season | |
| Oct 1, 2006 | 12–17 | Bills +5 | Bills +1.9 | Regular Season | |
| Oct 1, 2006 | 18–21 | Panthers +3 | Panthers +7.8 | Regular Season | |
| Oct 1, 2006 | 15–17 | Texans +2 | Dolphins +3.8 | Regular Season | |
| Oct 1, 2006 | 31–28 | Colts +3 | Colts +5.3 | Regular Season | |
| Oct 1, 2006 | 0–41 | Chiefs +41 | Chiefs +11.0 | Regular Season |