| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 22, 2006 | 31–13 | Vikings +18 | Seahawks +7.2 | Regular Season | |
| Oct 22, 2006 | 9–22 | Raiders +13 | Raiders +2.0 | Regular Season | |
| Oct 22, 2006 | 22–36 | Colts +14 | Colts +10.7 | Regular Season | |
| Oct 22, 2006 | 17–7 | Broncos +10 | Broncos +7.4 | Regular Season | |
| Oct 22, 2006 | 38–41 | Falcons +3 | Steelers +2.3 | Regular Season | |
| Oct 22, 2006 | 14–17 | Bengals +3 | Bengals +2.5 | Regular Season | |
| Oct 22, 2006 | 24–31 | Jets +7 | Jets +8.0 | Regular Season | |
| Oct 22, 2006 | 7–27 | Texans +20 | Jaguars +7.2 | Regular Season | |
| Oct 22, 2006 | 28–6 | Patriots +22 | Patriots +5.1 | Regular Season | |
| Oct 22, 2006 | 34–24 | Packers +10 | Dolphins +4.6 | Regular Season | |
| Oct 22, 2006 | 21–23 | Buccaneers +2 | Buccaneers +1.5 | Regular Season | |
| Oct 22, 2006 | 27–30 | Chiefs +3 | Chargers +0.3 | Regular Season |