| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 14, 2008 | 10–6 | Steelers +4 | Steelers +2.3 | Regular Season | |
| Sep 14, 2008 | 10–31 | Cardinals +21 | Cardinals +8.2 | Regular Season | |
| Sep 14, 2008 | 38–39 | Broncos +1 | Chargers +2.3 | Regular Season | |
| Sep 14, 2008 | 19–10 | Patriots +9 | Patriots +6.7 | Regular Season | |
| Sep 14, 2008 | 33–30 | 49ers +3 | Seahawks +9.4 | Regular Season | |
| Sep 14, 2008 | 9–24 | Buccaneers +15 | Buccaneers +5.7 | Regular Season | |
| Sep 14, 2008 | 18–15 | Colts +3 | Colts +2.5 | Regular Season | |
| Sep 14, 2008 | 20–16 | Bills +4 | Jaguars +5.0 | Regular Season | |
| Sep 14, 2008 | 17–20 | Panthers +3 | Bears +0.2 | Regular Season | |
| Sep 14, 2008 | 48–25 | Packers +23 | Packers +4.5 | Regular Season | |
| Sep 14, 2008 | 24–29 | Commanders +5 | Commanders +4.4 | Regular Season | |
| Sep 14, 2008 | 24–7 | Titans +17 | Bengals +2.0 | Regular Season | |
| Sep 14, 2008 | 23–8 | Raiders +15 | Chiefs +5.2 | Regular Season | |
| Sep 14, 2008 | 41–13 | Giants +28 | Giants +6.3 | Regular Season |