| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Nov 23, 2008 | 23–20 | Colts +3 | Chargers +2.0 | Regular Season | |
| Nov 23, 2008 | 37–29 | Giants +8 | Giants +2.2 | Regular Season | |
| Nov 23, 2008 | 20–17 | Commanders +3 | Commanders +0.6 | Regular Season | |
| Nov 23, 2008 | 28–45 | Falcons +17 | Panthers +1.1 | Regular Season | |
| Nov 23, 2008 | 31–10 | Raiders +21 | Broncos +10.0 | Regular Season | |
| Nov 23, 2008 | 30–12 | Vikings +18 | Jaguars +4.0 | Regular Season | |
| Nov 23, 2008 | 16–6 | Texans +10 | Browns +5.2 | Regular Season | |
| Nov 23, 2008 | 22–35 | Cowboys +13 | Cowboys +11.9 | Regular Season | |
| Nov 23, 2008 | 38–20 | Buccaneers +18 | Buccaneers +7.0 | Regular Season | |
| Nov 23, 2008 | 7–36 | Ravens +29 | Ravens +2.6 | Regular Season | |
| Nov 23, 2008 | 48–28 | Patriots +20 | Patriots +6.3 | Regular Season | |
| Nov 23, 2008 | 34–13 | Jets +21 | Titans +8.7 | Regular Season | |
| Nov 23, 2008 | 54–31 | Bills +23 | Bills +2.3 | Regular Season | |
| Nov 23, 2008 | 27–3 | Bears +24 | Bears +5.4 | Regular Season |