| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 19, 2010 | 14–38 | Colts +24 | Colts +5.5 | Regular Season | |
| Sep 19, 2010 | 14–28 | Jets +14 | Jets +2.1 | Regular Season | |
| Sep 19, 2010 | 30–27 | Texans +3 | Texans +2.3 | Regular Season | |
| Sep 19, 2010 | 13–38 | Chargers +25 | Chargers +8.5 | Regular Season | |
| Sep 19, 2010 | 14–31 | Broncos +17 | Broncos +3.6 | Regular Season | |
| Sep 19, 2010 | 14–16 | Raiders +2 | Raiders +5.1 | Regular Season | |
| Sep 19, 2010 | 27–20 | Bears +7 | Cowboys +7.2 | Regular Season | |
| Sep 19, 2010 | 14–10 | Dolphins +4 | Vikings +6.4 | Regular Season | |
| Sep 19, 2010 | 7–41 | Falcons +34 | Falcons +2.6 | Regular Season | |
| Sep 19, 2010 | 20–7 | Buccaneers +13 | Panthers +7.8 | Regular Season | |
| Sep 19, 2010 | 10–15 | Bengals +5 | Ravens +2.4 | Regular Season | |
| Sep 19, 2010 | 7–34 | Packers +27 | Packers +8.8 | Regular Season | |
| Sep 19, 2010 | 16–14 | Chiefs +2 | Browns +4.2 | Regular Season | |
| Sep 19, 2010 | 35–32 | Eagles +3 | Eagles +6.7 | Regular Season | |
| Sep 19, 2010 | 19–11 | Steelers +8 | Titans +2.0 | Regular Season |