| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Nov 14, 2021 | 41–14 | Chiefs +27 | Chiefs +2.5 | Regular Season | |
| Nov 14, 2021 | 30–13 | Eagles +17 | Broncos +4.8 | Regular Season | |
| Nov 14, 2021 | 0–17 | Packers +17 | Packers +8.0 | Regular Season | |
| Nov 14, 2021 | 34–10 | Panthers +24 | Cardinals +10.8 | Regular Season | |
| Nov 14, 2021 | 27–20 | Vikings +7 | Chargers +3.7 | Regular Season | |
| Nov 14, 2021 | 3–43 | Cowboys +40 | Cowboys +5.1 | Regular Season | |
| Nov 14, 2021 | 45–17 | Bills +28 | Bills +8.3 | Regular Season | |
| Nov 14, 2021 | 7–45 | Patriots +38 | Patriots +2.8 | Regular Season | |
| Nov 14, 2021 | 16–16 | Match tied | Steelers +13.6 | Regular Season | |
| Nov 14, 2021 | 17–23 | Colts +6 | Colts +13.3 | Regular Season | |
| Nov 14, 2021 | 21–23 | Titans +2 | Titans +2.7 | Regular Season | |
| Nov 14, 2021 | 19–29 | Commanders +10 | Buccaneers +7.2 | Regular Season |