| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 21, 2005 | 5–6 | Angels +1 | Angels +0.6 | Regular Season | |
| Sep 21, 2005 | 2–3 | Diamondbacks +1 | Dodgers +0.3 | Regular Season | |
| Sep 21, 2005 | 5–2 | Padres +3 | Padres +0.3 | Regular Season | |
| Sep 21, 2005 | 8–0 | Guardians +8 | White Sox +0.3 | Regular Season | |
| Sep 21, 2005 | 6–7 | Brewers +1 | Cubs +0.2 | Regular Season | |
| Sep 21, 2005 | 4–7 | Rays +3 | Red Sox +1.0 | Regular Season | |
| Sep 21, 2005 | 5–1 | Cardinals +4 | Cardinals +0.9 | Regular Season | |
| Sep 21, 2005 | 4–5 | Mets +1 | Marlins +0.1 | Regular Season | |
| Sep 21, 2005 | 3–2 | Mariners +1 | Blue Jays +0.4 | Regular Season | |
| Sep 21, 2005 | 10–6 | Phillies +4 | Braves +0.6 | Regular Season | |
| Sep 21, 2005 | 1–2 | Yankees +1 | Yankees +1.4 | Regular Season | |
| Sep 21, 2005 | 12–8 | Astros +4 | Astros +0.8 | Regular Season | |
| Sep 21, 2005 | 5–1 | Giants +4 | Giants +0.0 | Regular Season | |
| Sep 21, 2005 | 10–4 | Twins +6 | Athletics +0.8 | Regular Season | |
| Sep 21, 2005 | 3–4 | Royals +1 | Tigers +0.1 | Regular Season |