| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Oct 16, 2005 | 10–42 | Seahawks +32 | Seahawks +7.7 | Regular Season | |
| Oct 16, 2005 | 20–28 | Broncos +8 | Patriots +1.0 | Regular Season | |
| Oct 16, 2005 | 17–27 | Bills +10 | Bills +3.4 | Regular Season | |
| Oct 16, 2005 | 27–14 | Chargers +13 | Chargers +4.1 | Regular Season | |
| Oct 16, 2005 | 34–31 | Falcons +3 | Falcons +1.3 | Regular Season | |
| Oct 16, 2005 | 3–28 | Bears +25 | Vikings +0.3 | Regular Season | |
| Oct 16, 2005 | 31–23 | Bengals +8 | Bengals +0.3 | Regular Season | |
| Oct 16, 2005 | 3–16 | Ravens +13 | Ravens +6.1 | Regular Season | |
| Oct 16, 2005 | 21–20 | Panthers +1 | Panthers +2.3 | Regular Season | |
| Oct 16, 2005 | 13–16 | Cowboys +3 | Cowboys +2.7 | Regular Season | |
| Oct 16, 2005 | 23–17 | Jaguars +6 | Steelers +9.5 | Regular Season | |
| Oct 16, 2005 | 13–27 | Buccaneers +14 | Buccaneers +4.4 | Regular Season | |
| Oct 16, 2005 | 21–28 | Chiefs +7 | Chiefs +5.2 | Regular Season |