| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| May 21, 2010 | 1–4 | Dodgers +3 | Dodgers +0.3 | Regular Season | |
| May 21, 2010 | 8–15 | Mariners +7 | Mariners +0.2 | Regular Season | |
| May 21, 2010 | 1–6 | Athletics +5 | Athletics +0.1 | Regular Season | |
| May 21, 2010 | 6–8 | Diamondbacks +2 | Blue Jays +0.3 | Regular Season | |
| May 21, 2010 | 5–9 | Cardinals +4 | Angels +0.2 | Regular Season | |
| May 21, 2010 | 0–8 | White Sox +8 | White Sox +0.0 | Regular Season | |
| May 21, 2010 | 2–9 | Royals +7 | Rockies +0.4 | Regular Season | |
| May 21, 2010 | 3–15 | Twins +12 | Twins +0.9 | Regular Season | |
| May 21, 2010 | 1–2 | Rangers +1 | Rangers +0.5 | Regular Season | |
| May 21, 2010 | 1–2 | Astros +1 | Rays +0.8 | Regular Season | |
| May 21, 2010 | 2–1 | Yankees +1 | Yankees +1.0 | Regular Season | |
| May 21, 2010 | 7–0 | Braves +7 | Braves +0.6 | Regular Season | |
| May 21, 2010 | 5–3 | Orioles +2 | Nationals +0.3 | Regular Season | |
| May 21, 2010 | 1–5 | Phillies +4 | Phillies +0.2 | Regular Season | |
| May 21, 2010 | 7–4 | Reds +3 | Reds +0.1 | Regular Season |