| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 22, 2010 | 3–1 | Padres +2 | Dodgers +0.2 | Regular Season | |
| Sep 22, 2010 | 2–1 | Rangers +1 | Angels +0.3 | Regular Season | |
| Sep 22, 2010 | 4–8 | Diamondbacks +4 | Rockies +0.6 | Regular Season | |
| Sep 22, 2010 | 1–13 | Brewers +12 | Reds +0.1 | Regular Season | |
| Sep 22, 2010 | 0–2 | Cubs +2 | Giants +0.2 | Regular Season | |
| Sep 22, 2010 | 1–6 | Red Sox +5 | Red Sox +1.3 | Regular Season | |
| Sep 22, 2010 | 5–7 | Marlins +2 | Marlins +0.5 | Regular Season | |
| Sep 22, 2010 | 6–3 | Mariners +3 | Blue Jays +0.8 | Regular Season | |
| Sep 22, 2010 | 0–1 | Phillies +1 | Phillies +0.8 | Regular Season | |
| Sep 22, 2010 | 2–4 | Tigers +2 | Tigers +0.9 | Regular Season | |
| Sep 22, 2010 | 3–4 | Nationals +1 | Astros +0.4 | Regular Season | |
| Sep 22, 2010 | 7–2 | Rays +5 | Yankees +0.6 | Regular Season | |
| Sep 22, 2010 | 6–11 | Pirates +5 | Cardinals +0.9 | Regular Season | |
| Sep 22, 2010 | 4–3 | White Sox +1 | Athletics +0.2 | Regular Season | |
| Sep 22, 2010 | 1–5 | Twins +4 | Twins +1.4 | Regular Season |