| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| May 22, 2021 | 6–2 | Athletics +4 | Athletics +0.7 | Regular Season | |
| May 22, 2021 | 4–6 | Padres +2 | Padres +0.5 | Regular Season | |
| May 22, 2021 | 3–1 | Rays +2 | Rays +0.5 | Regular Season | |
| May 22, 2021 | 4–3 | Red Sox +1 | Red Sox +0.2 | Regular Season | |
| May 22, 2021 | 1–2 | Cardinals +1 | Cardinals +0.3 | Regular Season | |
| May 22, 2021 | 6–3 | Dodgers +3 | Dodgers +0.7 | Regular Season | |
| May 22, 2021 | 1–6 | Braves +5 | Braves +1.2 | Regular Season | |
| May 22, 2021 | 4–3 | Brewers +1 | Brewers +0.1 | Regular Season | |
| May 22, 2021 | 3–5 | Guardians +2 | Guardians +0.5 | Regular Season | |
| May 22, 2021 | 5–7 | Royals +2 | Royals +0.6 | Regular Season | |
| May 22, 2021 | 1–3 | Marlins +2 | Mets +0.3 | Regular Season | |
| May 22, 2021 | 9–12 | Nationals +3 | Nationals +1.2 | Regular Season | |
| May 22, 2021 | 4–8 | Rangers +4 | Astros +0.8 | Regular Season | |
| May 22, 2021 | 6–7 | Rockies +1 | Rockies +0.0 | Regular Season | |
| May 22, 2021 | 0–7 | Yankees +7 | Yankees +0.9 | Regular Season |