| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 22, 2021 | 8–6 | Giants +2 | Giants +0.4 | Regular Season | |
| Sep 22, 2021 | 9–2 | Braves +7 | Braves +0.9 | Regular Season | |
| Sep 22, 2021 | 4–1 | Mariners +3 | Athletics +0.5 | Regular Season | |
| Sep 22, 2021 | 9–5 | Astros +4 | Astros +0.7 | Regular Season | |
| Sep 22, 2021 | 5–10 | Rockies +5 | Dodgers +1.0 | Regular Season | |
| Sep 22, 2021 | 5–4 | Twins +1 | Cubs +0.1 | Regular Season | |
| Sep 22, 2021 | 10–2 | Cardinals +8 | Brewers +0.5 | Regular Season | |
| Sep 22, 2021 | 5–12 | Red Sox +7 | Red Sox +0.8 | Regular Season | |
| Sep 22, 2021 | 3–4 | Phillies +1 | Phillies +1.3 | Regular Season | |
| Sep 22, 2021 | 3–7 | Yankees +4 | Yankees +1.5 | Regular Season | |
| Sep 22, 2021 | 7–5 | Nationals +2 | Nationals +0.0 | Regular Season | |
| Sep 22, 2021 | 1–7 | Rays +6 | Rays +0.8 | Regular Season |