| Date | Matchup | Result | Winner | Model Projection | Stage |
|---|---|---|---|---|---|
| Sep 23, 2021 | 2–3 | Angels +1 | Astros +0.7 | Regular Season | |
| Sep 23, 2021 | 2–7 | Twins +5 | Blue Jays +0.1 | Regular Season | |
| Sep 23, 2021 | 0–3 | Orioles +3 | Rangers +0.2 | Regular Season | |
| Sep 23, 2021 | 6–12 | Phillies +6 | Phillies +1.0 | Regular Season | |
| Sep 23, 2021 | 3–2 | Nationals +1 | Reds +0.5 | Regular Season | |
| Sep 23, 2021 | 3–5 | Guardians +2 | Guardians +0.2 | Regular Season | |
| Sep 23, 2021 | 6–7 | Padres +1 | Giants +0.5 | Regular Season | |
| Sep 23, 2021 | 4–6 | Diamondbacks +2 | Braves +0.9 | Regular Season | |
| Sep 23, 2021 | 6–5 | Mariners +1 | Athletics +0.5 | Regular Season | |
| Sep 23, 2021 | 7–5 | Dodgers +2 | Dodgers +1.0 | Regular Season | |
| Sep 23, 2021 | 8–5 | Cardinals +3 | Brewers +0.4 | Regular Season | |
| Sep 23, 2021 | 7–2 | White Sox +5 | Guardians +0.2 | Regular Season |