Records since the 1976 season.
| Matchup | Record | Win % | Vs Expected | Games |
|---|---|---|---|---|
| 76ers Celtics | 130-164-4 | 44.2% | +3.9 | 298 |
| 76ers Knicks | 131-121-4 | 52.0% | -5.5 | 256 |
| 76ers Bucks | 125-118-3 | 51.4% | +2.7 | 246 |
| 76ers Wizards | 149-94-3 | 61.3% | +2.5 | 246 |
| 76ers Nets | 142-97-4 | 59.4% | -4.0 | 243 |
| 76ers Pistons | 114-111-3 | 50.7% | -3.1 | 228 |
| 76ers Pacers | 122-98-4 | 55.5% | +3.1 | 224 |
| 76ers Hawks | 106-114-3 | 48.2% | -13.3 | 223 |
| 76ers Bulls | 115-102-4 | 53.0% | +3.7 | 221 |
| 76ers Cavaliers | 113-100-3 | 53.1% | -3.7 | 216 |
| 76ers Heat | 76-86-4 | 46.9% | +3.4 | 166 |
| 76ers Magic | 61-89-3 | 40.7% | -11.5 | 153 |
| 76ers Raptors | 62-77-4 | 44.6% | -6.6 | 143 |
| 76ers Hornets | 72-62-4 | 53.7% | +0.4 | 138 |
| 76ers Lakers | 59-70-2 | 45.7% | +3.9 | 131 |
| 76ers Rockets | 60-58-2 | 50.8% | +1.7 | 120 |
| 76ers Spurs | 50-66-2 | 43.1% | -1.7 | 118 |
| 76ers Trail Blazers | 56-57-2 | 49.6% | +2.6 | 115 |
| 76ers Clippers | 69-44-2 | 61.1% | +4.1 | 115 |
| 76ers Jazz | 52-57-2 | 47.7% | -3.0 | 111 |
| 76ers Kings | 66-42-2 | 61.1% | +2.4 | 110 |
| 76ers Thunder | 50-58-2 | 46.3% | -1.2 | 110 |
| 76ers Warriors | 51-57-2 | 47.2% | -7.2 | 110 |
| 76ers Suns | 43-62-2 | 41.0% | -6.7 | 107 |
| 76ers Nuggets | 54-48-2 | 52.9% | +1.9 | 104 |
| 76ers Mavericks | 46-43-2 | 51.7% | +1.1 | 91 |
| 76ers Timberwolves | 36-34-2 | 51.4% | -0.7 | 72 |
| 76ers Grizzlies | 29-30-2 | 49.2% | -3.1 | 61 |
| 76ers Pelicans | 28-27-2 | 50.9% | -0.9 | 57 |
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